Biomass based wood adhesives are generally neutral substances, so the selected preservatives can be stable under strong acid and alkali conditions to maintain the drug concentration during the storage of adhesives. Jinan antiseptic wood, such as sodium pentachlorophenol traditionally used, is easy to decompose when exposed to light and heat, and chlorothalonil is decomposed in strong alkaline solution to release HCl. These characteristics are also reference indicators for selection of anti-corrosion agents.
The BIT series industrial bactericidal products successfully developed in the 1970s include BIT raw powder, PT solution, BTC solution, BTG solution, BTX solution, etc. The main active ingredient is 1,2-benzoisothiazoline-3-one. It is soluble in the range of pH 4~12 and stable in the presence of ammonia. It has significant effect on bacteria, mold and yeast, and has high sterilization efficiency. 0.005%~0.05% can be added. Stable performance at 200? The germicidal efficacy remains unchanged under high temperature. Easy to use, no pollution, no corrosion to metal. Low toxicity, LD50>1400mg · kg-1. Therefore, it is not only used in bean glue storage, even after hot pressing (100~140?) It is also OK to maintain the efficacy to the anti-corrosion of the plate; The antimicrobials must be antimetabolic with the ability of anti microbial enzymolysis in order to extend the antibacterial action time. For example, bromo cinnamaldehyde is not a natural organic substance that is enzymatically synthesized, and is not easy to be enzymatically decomposed in microorganisms. The antibacterial period can be increased by 350 times.
Mechanism and Countermeasure of Microbial Drug Resistance Formation
The slight mutation of microbial gene can form a new physiological metabolic pathway of drug resistance. The core of emerging anti-corrosion technology is to try to interfere with the self balance regulation mechanism evolved by microorganisms to survive against various environments. Due to the narrow scope of antibacterial and insect repellent of a single preservative, it is easy to induce microbial resistance in a short time. In order to give full play to the Z-effect of preservatives and minimize their negative effects, the use of preservatives has become a worldwide trend, and has achieved good results. Generally, two or more preservatives with additive or synergistic effects are reasonably mixed in a certain proportion, which can not only overcome the shortcomings of single preservatives, but also produce some new characteristics. If the antibacterial agents with different antibacterial mechanisms are combined to produce an ultra broad antibacterial spectrum that can not be achieved by a single agent, most of the mutants will lose the basis for survival. Thus, it interferes with the formation of microbial drug resistance, and receives Z's good anti-corrosion effect.